Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.33 |
| ▸ | HTR2C | P28335 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.32 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | RAF1 | P04049 | 2/20 | 0.31 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.31 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.31 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.31 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.31 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.31 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30782850 | 1.00 | KDM4C (0.33) | KDM4CHTR2CSLC6A4PDK2P2RX7 | |
| SCHEMBL27214623 | 1.00 | KDM4C (0.33) | KDM4CHTR2CSLC6A4PDK2P2RX7 | |
| SCHEMBL30782853 | 1.00 | KDM4C (0.33) | KDM4CHTR2CSLC6A4PDK2P2RX7 | |
| SCHEMBL30782890 | 1.00 | KDM4C (0.33) | KDM4CHTR2CSLC6A4PDK2P2RX7 | |
| SCHEMBL29923128 | 0.89 | BRD4 (0.33) | KDM4CHTR2CSLC6A4UCHL1 | |
| SCHEMBL29923610 | 0.89 | BRD4 (0.33) | KDM4CHTR2CSLC6A4UCHL1 | |
| SCHEMBL27231300 | 0.89 | KDM4C (0.38) | KDM4CP2RX7GRIN1GRIN2BPARP15 | |
| SCHEMBL27214582 | 0.89 | KDM4C (0.38) | KDM4CP2RX7GRIN1GRIN2BPARP15 | |
| SCHEMBL29923492 | 0.88 | CPT2 (0.34) | KDM4CHTR2CSLC6A4PDK2HTR2A | |
| SCHEMBL27214562 | 0.88 | CPT2 (0.34) | KDM4CHTR2CSLC6A4PDK2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022217232-A1 | CHROMANS AND BENZOFURANS AS 5-HT1A AND TAAR1 AGONISTS | SUNOVION PHARMACEUTICALS INC. (US) | 2022-10-13 | — | — | WO | disclosed |