Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 20/20 | 0.58 |
| ▸ | MTOR | P42345 | 10/20 | 0.58 |
| ▸ | RICTOR | Q6R327 | 5/20 | 0.58 |
| ▸ | RPTOR | Q8N122 | 5/20 | 0.58 |
| ▸ | MAPKAP1 | Q9BPZ7 | 5/20 | 0.58 |
| ▸ | MLST8 | Q9BVC4 | 5/20 | 0.58 |
| ▸ | PIK3R1 | P27986 | 8/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.44 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.44 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27086818 | 1.00 | PIK3CA (0.58) | PIK3CAMTORRICTORRPTORMAPKAP1 | |
| SCHEMBL27429217 | 0.93 | PIK3CA (0.58) | PIK3CAMTORRICTORRPTORMAPKAP1 | |
| SCHEMBL27429219 | 0.85 | PIK3CA (0.61) | PIK3CAMTORRICTORRPTORMAPKAP1 | |
| SCHEMBL27429334 | 0.85 | PIK3CA (0.60) | PIK3CAMTORRICTORRPTORMAPKAP1 | |
| SCHEMBL29924195 | 0.84 | PIK3CA (0.62) | PIK3CAMTORRICTORRPTORMAPKAP1 | |
| SCHEMBL27086707 | 0.84 | PIK3CA (0.62) | PIK3CAMTORRICTORRPTORMAPKAP1 | |
| SCHEMBL27429232 | 0.83 | PIK3CA (0.63) | PIK3CAMTORRICTORRPTORMAPKAP1 | |
| SCHEMBL29921488 | 0.83 | PIK3CA (0.71) | PIK3CAMTORRICTORRPTORMAPKAP1 | |
| SCHEMBL27086859 | 0.83 | PIK3CA (0.71) | PIK3CAMTORRICTORRPTORMAPKAP1 | |
| SCHEMBL27429305 | 0.83 | PIK3CA (0.59) | PIK3CAMTORRICTORRPTORMAPKAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4320110-A1 | TRIAZINE DERIVATIVE AS COVALENT INHIBITORS OF PI3K | Universität Basel (CH) | 2024-02-14 | — | — | EP | disclosed |
| WO-2022214701-A1 | TRIAZINE DERIVATIVE AS COVALENT INHIBITORS OF PI3K | UNIVERSITÄT BASEL (CH) | 2022-10-13 | — | — | WO | disclosed |