Formic Acid

Formic Acid

SCHEMBL29924804

CCN(CC)CCCNC(=O)c1ccc2c(c1)sc1nc(-c3cccc(CN)c3)cn12.CCN(CC)CCCNC(=O)c1ccc2c(c1)sc1nc(-c3cccc(CN)c3)cn12.O=CO

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.70
TP53 P04637 6/20 0.58
LMNA P02545 2/20 0.57
THRB P10828 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30086010 0.97 MAPT (0.75) MAPTTP53LMNATHRB
SCHEMBL24619547 0.97 MAPT (0.75) MAPTTP53LMNATHRB
SCHEMBL29924543 0.90 MAPT (0.82) MAPTTP53LMNATHRB
SCHEMBL24619939 0.90 MAPT (0.82) MAPTTP53LMNATHRB
Formic Acid SCHEMBL30086052 0.88 MAPT (0.71) MAPTTP53LMNATHRB
Formic Acid SCHEMBL30086112 0.87 MAPT (0.63) MAPTTP53LMNATHRB
SCHEMBL24105969 0.87 MAPT (0.85) MAPTTP53LMNATHRB
SCHEMBL30086019 0.87 MAPT (0.85) MAPTTP53LMNATHRB
Formic Acid SCHEMBL30537870 0.87 MAPT (0.79) MAPTTP53LMNATHRB
Formic Acid SCHEMBL29925138 0.86 MAPT (0.81) MAPTTP53LMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4274569-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER Anima Biotech Inc. (US) 2023-11-15 EP disclosed
US-20220370431-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2022-11-24 US disclosed
WO-2022150316-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2022-07-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220370431-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER MYC, MYCBP, MYCBP2 MAPT 3215/4885TP53 96/4885LMNA 1484/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.