⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11426097 | 0.79 | — | — | |
| SCHEMBL22345900 | 0.78 | — | — | |
| SCHEMBL6633605 | 0.78 | TP53 (0.42) | — | |
| SCHEMBL127653 | 0.74 | — | — | |
| SCHEMBL10815842 | 0.74 | — | — | |
| SCHEMBL6632157 | 0.71 | TP53 (0.36) | — | |
| SCHEMBL11681718 | 0.70 | — | — | |
| SCHEMBL27692353 | 0.70 | — | — | |
| SCHEMBL27673635 | 0.70 | — | — | |
| SCHEMBL21268828 | 0.69 | TP53 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109963922-B | Aldehyde scavenger and method for removing aldehyde | 东曹株式会社 | 2022-09-23 | — | — | CN | disclosed |
| US-20200061225-A1 | ALDEHYDE SCAVENGER AND METHOD FOR REMOVING ALDEHYDES | TOSOH CORPORATION (JP) | 2020-02-27 | — | — | US | disclosed |
| EP-3564334-A1 | ALDEHYDE SCAVENGER AND ALDEHYDE REMOVAL METHOD | Tosoh Corporation (JP) | 2019-11-06 | — | — | EP | disclosed |
| CN-109963922-A | Aldehyde agent for capturing and aldehyde minimizing technology | 东曹株式会社 | 2019-07-02 | — | — | CN | disclosed |
| US-20100173896-A1 | Organic Compounds | SAKAKI JUNICHI | 2010-07-08 | — | — | US | disclosed |
| US-7709470-B2 | 11-phenyl-dibenzodiazepine derivatives as RXR-antagonists | NOVARTIS AG (CH) | 2010-05-04 | — | — | US | disclosed |
| US-20070043029-A1 | 11-Phenyl-dibenzodiazepine derivatives as rxr-antagonists | NOVARTIS AG (CH) | 2007-02-22 | — | — | US | disclosed |
| EP-0945445-B9 | 1,5-BENZODIAZEPINE DERIVATIVES | ZERIA PHARM CO LTD (JP) | 2005-12-28 | — | — | EP | disclosed |
| US-20050124614-A1 | 3,4-Dihydroisoquinolin-1-one derivatives as inducers of apoptosis | AXYS PHARMACEUTICALS, INC. (US) | 2005-06-09 | — | — | US | disclosed |
| CN-1130351-C | 1,5-benzodiazepine derivatives | ZERIA PHARM CO LTD (JP) | 2003-12-10 | — | — | CN | disclosed |
| EP-0945445-B1 | 1,5-BENZODIAZEPINE DERIVATIVES | ZERIA PHARM CO LTD (JP) | 2003-09-03 | — | — | EP | disclosed |
| US-6239131-B1 | WHICH HAVE GASTRIN AND/OR CCK-B (CHOLECYSTOKININ-B) RECEPTOR ANTAGONISM, USEFUL AS REMEDIES FOR GASTRIC ULCER AND GASTROINTESTINAL MOVEMENT DISORDER. | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-29 | — | — | US | disclosed |
| CN-1246850-A | 1,5-benzodiazepine derivatives | ZERIA PHARM CO LTD (JP) | 2000-03-08 | — | — | CN | disclosed |
| EP-0945445-A1 | 1,5-BENZODIAZEPINE DERIVATIVES | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |