SCHEMBL29924935

SCHEMBL29924935

CCN(CC)CCCNC(=O)c1ccc2c(c1)sc1nc(-c3ccc(C(C)C)cc3)cn12

nearest known ligand 0.82

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 7/20 0.82
▸ LMNA P02545 2/20 0.64
▸ TP53 P04637 5/20 0.61
▸ THRB P10828 2/20 0.57
▸ POLB P06746 1/20 0.56
▸ SMN1; SMN2 Q16637 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24740985 1.00 MAPT (0.82) MAPTLMNATP53THRBPOLB
Formic Acid SCHEMBL30086006 0.97 MAPT (0.78) MAPTLMNATP53THRBPOLB
SCHEMBL29925306 0.92 MAPT (0.76) MAPTLMNATP53THRB
SCHEMBL24619697 0.92 MAPT (0.76) MAPTLMNATP53THRB
SCHEMBL29925050 0.91 MAPT (0.85) MAPTLMNATP53THRBPOLB
SCHEMBL24619448 0.91 MAPT (0.85) MAPTLMNATP53THRBPOLB
SCHEMBL24741676 0.91 MAPT (0.79) MAPTLMNATP53THRBPOLB
SCHEMBL30086080 0.91 MAPT (0.79) MAPTLMNATP53THRBPOLB
SCHEMBL24740856 0.91 MAPT (0.81) MAPTLMNATP53THRBPOLB
SCHEMBL30086003 0.91 MAPT (0.81) MAPTLMNATP53THRBPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4274569-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER Anima Biotech Inc. (US) 2023-11-15 — — EP disclosed
WO-2022150316-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2022-07-14 — — WO disclosed
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