SCHEMBL29924965

SCHEMBL29924965

N=C(N)NCCC[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CCCNC(=N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ ACE P12821 2/20 0.55
▸ ERAP2 Q6P179 5/20 0.53
▸ ERAP1 Q9NZ08 4/20 0.53
▸ LNPEP Q9UIQ6 4/20 0.53
▸ NPY1R P25929 2/20 0.52
▸ NPY2R P49146 2/20 0.52
▸ NPY4R P50391 2/20 0.52
▸ ECE1 P42892 3/20 0.52
▸ ALOX15 P16050 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29924961 1.00 ACE (0.55) ACEERAP2ERAP1LNPEPNPY1R
SCHEMBL29662004 1.00 ACE (0.55) ACEERAP2ERAP1LNPEPNPY1R
SCHEMBL30389391 0.99 ACE (0.54) ACEERAP2ERAP1LNPEPNPY1R
SCHEMBL30462544 0.99 ACE (0.54) ACEERAP2ERAP1LNPEPNPY1R
SCHEMBL30389486 0.99 ACE (0.54) ACEERAP2ERAP1LNPEPNPY1R
SCHEMBL30389400 0.99 ACE (0.54) ACEERAP2ERAP1LNPEPNPY1R
SCHEMBL29837379 0.99 ACE (0.54) ACEERAP2ERAP1LNPEPNPY1R
SCHEMBL30646171 0.99 ACE (0.54) ACEERAP2ERAP1LNPEPNPY1R
SCHEMBL30945412 0.99 ACE (0.54) ACEERAP2ERAP1LNPEPNPY1R
SCHEMBL30388732 0.99 ACE (0.54) ACEERAP2ERAP1LNPEPNPY1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220289794-A1 SYNTHETIC ANTIMICROBIAL PEPTIDES AJK BIOPHARMACEUTICAL LLC (US) 2022-09-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220289794-A1 SYNTHETIC ANTIMICROBIAL PEPTIDES VIP, HM13, NGLY1 ACE 2034/4885ERAP2 506/4885ERAP1 208/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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