Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 11/20 | 0.53 |
| ▸ | TP53 | P04637 | 6/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 8/20 | 0.47 |
| ▸ | NPC1 | O15118 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | KDM5A | P29375 | 1/20 | 0.47 |
| ▸ | KDM5C | P41229 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29925367 | 0.87 | SMN1; SMN2 (0.48) | SMN1; SMN2TP53THRBF2RL3RAB9A | |
| SCHEMBL5012213 | 0.86 | TP53 (0.50) | SMN1; SMN2TP53THRBF2RL3RAB9A | |
| SCHEMBL1033020 | 0.85 | TP53 (0.57) | SMN1; SMN2TP53THRBF2RL3RAB9A | |
| SCHEMBL27362665 | 0.85 | TP53 (0.50) | SMN1; SMN2TP53THRBRAB9ANPC1 | |
| SCHEMBL7498217 | 0.83 | TP53 (0.42) | SMN1; SMN2TP53THRBRAB9ANPC1 | |
| SCHEMBL29924707 | 0.82 | MAPT (0.53) | SMN1; SMN2TP53THRBF2RL3RAB9A | |
| SCHEMBL27361295 | 0.80 | KMT2A (0.51) | SMN1; SMN2TP53RAB9ANPC1KDM4E | |
| SCHEMBL12997562 | 0.80 | SMN1; SMN2 (0.57) | SMN1; SMN2TP53THRBF2RL3RAB9A | |
| SCHEMBL27362944 | 0.79 | SMN1; SMN2 (0.41) | SMN1; SMN2TP53THRBRAB9ANPC1 | |
| SCHEMBL2998562 | 0.77 | WDR91 (0.44) | SMN1; SMN2RAB9ANPC1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4274569-A1 | C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER | Anima Biotech Inc. (US) | 2023-11-15 | — | — | EP | disclosed |
| CN-116635028-A | Modulators of c-MYC mRNA translation and their use in the treatment of cancer | 艾尼莫生物科技公司 | 2023-08-22 | — | — | CN | disclosed |
| WO-2022150316-A1 | C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER | ANIMA BIOTECH INC. (US) | 2022-07-14 | — | — | WO | disclosed |