Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28598682 | 1.00 | CD274 (0.41) | CD274PDCD1 | |
| SCHEMBL27084399 | 0.96 | CD274 (0.40) | CD274PDCD1 | |
| SCHEMBL30267002 | 0.96 | CD274 (0.40) | CD274PDCD1 | |
| SCHEMBL30267183 | 0.86 | CD274 (0.43) | CD274PDCD1 | |
| SCHEMBL28596509 | 0.86 | CD274 (0.43) | CD274PDCD1 | |
| SCHEMBL20721089 | 0.83 | CD274 (0.47) | CD274PDCD1 | |
| SCHEMBL29925700 | 0.82 | CD274 (0.56) | CD274PDCD1 | |
| SCHEMBL19897846 | 0.81 | CD274 (0.54) | CD274PDCD1 | |
| SCHEMBL21357311 | 0.81 | CD274 (0.46) | CD274PDCD1 | |
| SCHEMBL30335521 | 0.81 | CD274 (0.46) | CD274PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117561246-A | Novel biphenyl derivative, preparation method and medical application thereof | 西安新通药物研究股份有限公司 | 2024-02-13 | — | — | CN | disclosed |
| CN-113461668-B | Novel biphenyl derivative, preparation method and medical application thereof | 西安新通药物研究股份有限公司 | 2022-12-09 | — | — | CN | disclosed |
| WO-2022228286-A1 | NOVEL BIPHENYL DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICINAL USE THEREOF | 西安新通药物研究股份有限公司 | 2022-11-03 | — | — | WO | disclosed |