Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 7/20 | 0.87 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.87 |
| ▸ | FGFR2 | P21802 | 3/20 | 0.87 |
| ▸ | FGFR3 | P22607 | 3/20 | 0.87 |
| ▸ | JAK3 | P52333 | 7/20 | 0.80 |
| ▸ | EGFR | P00533 | 7/20 | 0.63 |
| ▸ | JAK2 | O60674 | 1/20 | 0.61 |
| ▸ | JAK1 | P23458 | 1/20 | 0.61 |
| ▸ | TYK2 | P29597 | 1/20 | 0.61 |
| ▸ | BTK | Q06187 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17857061 | 0.93 | FGFR4 (1.00) | FGFR4FGFR1FGFR2FGFR3JAK3 | |
| SCHEMBL17209826 | 0.89 | JAK3 (1.00) | FGFR4FGFR1FGFR2FGFR3JAK3 | |
| SCHEMBL24490215 | 0.87 | FGFR4 (0.78) | FGFR4FGFR1FGFR2FGFR3JAK3 | |
| SCHEMBL19441991 | 0.85 | FGFR4 (0.84) | FGFR4FGFR1FGFR2FGFR3JAK3 | |
| SCHEMBL17974121 | 0.84 | FGFR4 (0.66) | FGFR4FGFR1FGFR2FGFR3JAK3 | |
| SCHEMBL17857066 | 0.84 | FGFR4 (0.82) | FGFR4FGFR1FGFR2FGFR3JAK3 | |
| SCHEMBL17209831 | 0.83 | JAK3 (1.00) | FGFR4FGFR1FGFR2FGFR3JAK3 | |
| SCHEMBL16071909 | 0.83 | FGFR4 (0.64) | FGFR4FGFR1FGFR2FGFR3JAK3 | |
| SCHEMBL17209937 | 0.81 | JAK3 (0.84) | FGFR4FGFR1FGFR2FGFR3JAK3 | |
| SCHEMBL17210135 | 0.81 | JAK3 (1.00) | FGFR4FGFR1FGFR2FGFR3JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250066860-A1 | METHODS AND MATERIALS FOR ASSESSING AND TREATING CANCER | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK | 2025-02-27 | — | — | US | disclosed |
| CN-111868260-B | Methods and materials for assessing and treating cancer | 约翰斯霍普金斯大学 | 2025-02-21 | — | — | CN | disclosed |
| US-12195803-B2 | Methods and materials for assessing and treating cancer | THE JOHNS HOPKINS UNIVERSITY (US) | 2025-01-14 | — | — | US | disclosed |
| US-20250000908-A1 | METHODS FOR PREPARING AND ADMINISTERING CRYOPRESERVED PLATELETS AND PLATELET DERIVATIVES LOADED WITH ANTI-CANCER DRUGS | CELLPHIRE, INC. (US) | 2025-01-02 | — | — | US | disclosed |
| US-11965178-B2 | Platelets loaded with anti-cancer agents | CELLPHIRE, INC. (US) | 2024-04-23 | — | — | US | disclosed |
| US-20230248771-A1 | PLATELETS LOADED WITH ANTI-CANCER AGENTS | CELLPHIRE, INC. (US) | 2023-08-10 | — | — | US | disclosed |
| US-20230149468-A1 | PLATELET DERIVED EXTRACELLULAR VESICLES | CELLPHIRE, INC. (US) | 2023-05-18 | — | — | US | disclosed |
| WO-2021232015-A9 | PLATELET DERIVED EXTRACELLULAR VESICLES | CELLPHIRE, INC. (US) | 2022-09-15 | — | — | WO | disclosed |