Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 19/20 | 0.65 |
| ▸ | DDB1 | Q16531 | 11/20 | 0.49 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29132245 | 1.00 | CRBN (0.65) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL29132166 | 0.90 | CRBN (0.69) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL29927344 | 0.90 | CRBN (0.69) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL30144407 | 0.89 | CRBN (0.72) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL29259997 | 0.89 | CRBN (0.72) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL29927626 | 0.87 | CRBN (0.65) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL29132104 | 0.87 | CRBN (0.65) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL30619732 | 0.87 | CRBN (0.70) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| Hydrochloric Acid SCHEMBL31491158 | 0.86 | CRBN (0.69) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL29132305 | 0.86 | CRBN (0.69) | CRBNDDB1IKZF3ALDH1A1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4308557-A1 | INDAZOLE BASED COMPOUNDS AND ASSOCIATED METHODS OF USE | Arvinas Operations, Inc. (US) | 2024-01-24 | — | — | EP | disclosed |
| WO-2022198112-A1 | INDAZOLE BASED COMPOUNDS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2022-09-22 | — | — | WO | disclosed |