Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 16/20 | 0.89 |
| ▸ | KDR | P35968 | 8/20 | 0.89 |
| ▸ | INSR | P06213 | 7/20 | 0.89 |
| ▸ | CCR4 | P51679 | 3/20 | 0.53 |
| ▸ | GALR1 | P47211 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4984043 | 1.00 | AXL (0.89) | AXLKDRINSRCCR4GALR1 | |
| SCHEMBL4243304 | 0.94 | AXL (1.00) | AXLKDRINSRCCR4 | |
| SCHEMBL4238608 | 0.87 | AXL (0.79) | AXLKDRINSR | |
| SCHEMBL29927936 | 0.87 | AXL (0.79) | AXLKDRINSR | |
| SCHEMBL4982458 | 0.87 | AXL (0.68) | AXLKDRINSRCCR4 | |
| SCHEMBL29928357 | 0.86 | AXL (0.76) | AXLKDRINSR | |
| SCHEMBL4986670 | 0.86 | AXL (0.76) | AXLKDRINSR | |
| SCHEMBL4254711 | 0.86 | AXL (0.85) | AXLKDRINSRCCR4 | |
| SCHEMBL4983688 | 0.86 | AXL (0.66) | AXLKDRINSRCCR4 | |
| SCHEMBL4985229 | 0.85 | AXL (0.65) | AXLKDRINSRCCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110551105-B | Substituted triazoles useful as AXL inhibitors | 里格尔制药公司 | 2022-10-18 | — | — | CN | claimed |
| CN-110551105-B | Substituted triazoles useful as AXL inhibitors | 里格尔制药公司 | 2022-10-18 | — | — | CN | disclosed |