Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 13/20 | 1.00 |
| ▸ | AXL | P30530 | 12/20 | 1.00 |
| ▸ | INSR | P06213 | 6/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4236047 | 1.00 | BACE1 (1.00) | BACE1AXLINSR | |
| SCHEMBL4248294 | 0.90 | AXL (1.00) | BACE1AXLINSR | |
| SCHEMBL29927868 | 0.90 | AXL (1.00) | BACE1AXLINSR | |
| SCHEMBL3965030 | 0.87 | BACE1 (0.77) | BACE1AXLINSR | |
| SCHEMBL29928453 | 0.86 | AXL (0.75) | BACE1AXLINSR | |
| SCHEMBL4992416 | 0.86 | AXL (0.75) | BACE1AXLINSR | |
| SCHEMBL29928959 | 0.85 | BACE1 (1.00) | BACE1AXLINSR | |
| SCHEMBL4994697 | 0.85 | BACE1 (1.00) | BACE1AXLINSR | |
| SCHEMBL4991682 | 0.84 | AXL (0.73) | BACE1AXLINSR | |
| SCHEMBL4989689 | 0.84 | AXL (0.73) | BACE1AXLINSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110551105-B | Substituted triazoles useful as AXL inhibitors | 里格尔制药公司 | 2022-10-18 | — | — | CN | claimed |
| CN-110551105-B | Substituted triazoles useful as AXL inhibitors | 里格尔制药公司 | 2022-10-18 | — | — | CN | disclosed |