SCHEMBL29928338

SCHEMBL29928338

C1CC(O[C@@H]2CC[C@@H](OC3CCNCC3)C2)CCN1

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HRH1 P35367 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25133665 1.00 HRH1 (0.37) HRH1
SCHEMBL13162561 0.91 HRH1 (0.41) HRH1
SCHEMBL29132213 0.91 HRH1 (0.41) HRH1
SCHEMBL25133943 0.91 HRH1 (0.41) HRH1
SCHEMBL8018672 0.88 HRH1 (0.42) HRH1
SCHEMBL23205156 0.80 HRH1 (0.32) HRH1
SCHEMBL23205160 0.80 HRH1 (0.32) HRH1
SCHEMBL22374848 0.80
SCHEMBL77267 0.80 HRH1 (0.38) HRH1
SCHEMBL86873 0.80 HRH1 (0.38) HRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4308557-A1 INDAZOLE BASED COMPOUNDS AND ASSOCIATED METHODS OF USE Arvinas Operations, Inc. (US) 2024-01-24 EP disclosed
CN-117321046-A Indazole-based compounds and related methods of use 阿维纳斯企业公司 2023-12-29 CN disclosed
WO-2022198112-A1 INDAZOLE BASED COMPOUNDS AND ASSOCIATED METHODS OF USE ARVINAS OPERATIONS, INC. (US) 2022-09-22 WO disclosed