Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 12/20 | 0.71 |
| ▸ | AXL | P30530 | 12/20 | 0.61 |
| ▸ | INSR | P06213 | 4/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29927647 | 0.90 | AXL (0.71) | BACE1AXLINSR | |
| SCHEMBL29929719 | 0.85 | BACE1 (0.68) | BACE1AXLINSR | |
| SCHEMBL4252593 | 0.83 | AXL (0.81) | BACE1AXLINSR | |
| SCHEMBL4996645 | 0.83 | BACE1 (1.00) | BACE1AXLINSR | |
| SCHEMBL4240361 | 0.80 | AXL (0.68) | BACE1AXLINSR | |
| SCHEMBL4997740 | 0.79 | BACE1 (1.00) | BACE1AXLINSR | |
| SCHEMBL4237828 | 0.76 | AXL (1.00) | BACE1AXLINSR | |
| SCHEMBL4997728 | 0.76 | AXL (0.77) | BACE1AXLINSR | |
| SCHEMBL1167180 | 0.75 | AXL (0.61) | BACE1AXLINSR | |
| SCHEMBL4044502 | 0.75 | FLT3 (0.65) | AXLINSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110551105-B | Substituted triazoles useful as AXL inhibitors | 里格尔制药公司 | 2022-10-18 | — | — | CN | claimed |
| CN-110551105-B | Substituted triazoles useful as AXL inhibitors | 里格尔制药公司 | 2022-10-18 | — | — | CN | disclosed |