SCHEMBL29928642

SCHEMBL29928642

CCOC(=O)CCN1CCN(c2ccc(Oc3cc(CN4CCC(CNC(C)=O)CC4)cc(-c4cc(Cl)cc(Cl)c4)n3)cn2)CC1

nearest known ligand 0.85

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ FURIN P09958 20/20 0.85

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21551143 1.00 FURIN (0.85) FURIN
SCHEMBL21551464 0.97 FURIN (0.81) FURIN
SCHEMBL21551655 0.96 FURIN (0.78) FURIN
SCHEMBL29928035 0.94 FURIN (0.89) FURIN
SCHEMBL30109155 0.94 FURIN (0.89) FURIN
SCHEMBL21550688 0.94 FURIN (0.89) FURIN
SCHEMBL21550881 0.94 FURIN (0.86) FURIN
SCHEMBL21551230 0.94 FURIN (0.85) FURIN
SCHEMBL30931791 0.92 FURIN (0.83) FURIN
SCHEMBL21551406 0.92 FURIN (0.83) FURIN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3790871-B1 FURIN INHIBITORS GLAXOSMITHKLINE IP DEV LTD (GB) 2024-01-24 — — EP disclosed
EP-4058021-A1 SMALL MOLECULE FURIN INHIBITORS FOR TREATING INFECTIOUS DISEASES BP Asset V, Inc. (US) 2022-09-21 — — EP disclosed
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