Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 13/20 | 0.58 |
| ▸ | CACNA1I | Q9P0X4 | 4/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.51 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | CCR3 | P51677 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21564374 | 1.00 | FURIN (0.58) | FURINCACNA1IKCNH2ACHECCR3 | |
| SCHEMBL21551424 | 0.90 | FURIN (0.57) | FURINCACNA1IKCNH2 | |
| SCHEMBL26077237 | 0.90 | FURIN (0.58) | FURINCACNA1IKCNH2CCR3 | |
| Hydrochloric Acid SCHEMBL21551130 | 0.89 | FURIN (0.56) | FURINCACNA1IKCNH2 | |
| SCHEMBL31540760 | 0.85 | CACNA1I (0.58) | FURINCACNA1IKCNH2ACHECCR3 | |
| SCHEMBL21551150 | 0.84 | FURIN (0.53) | FURIN | |
| SCHEMBL30931760 | 0.84 | FURIN (0.53) | FURIN | |
| SCHEMBL30931839 | 0.83 | CACNA1I (0.54) | FURINCACNA1IKCNH2ACHECCR3 | |
| SCHEMBL21550897 | 0.83 | CACNA1I (0.54) | FURINCACNA1IKCNH2ACHECCR3 | |
| Hydrochloric Acid SCHEMBL29891250 | 0.82 | CACNA1I (0.53) | FURINCACNA1IKCNH2ACHECCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112384509-B | Furin inhibitors | 葛兰素史密斯克莱知识产权发展有限公司 | 2024-04-30 | — | — | CN | disclosed |
| EP-4058021-A1 | SMALL MOLECULE FURIN INHIBITORS FOR TREATING INFECTIOUS DISEASES | BP Asset V, Inc. (US) | 2022-09-21 | — | — | EP | disclosed |