SCHEMBL29928675

SCHEMBL29928675

CC(=O)NCC1CCN(Cc2cc(Oc3ccc(N4CCN(CC(=O)O)CC4)nc3)nc(-c3cc(Cl)cc(Cl)c3)c2)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ FURIN P09958 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21551145 1.00 FURIN (1.00) FURIN
SCHEMBL29928209 0.93 FURIN (1.00) FURIN
SCHEMBL21551395 0.93 FURIN (1.00) FURIN
SCHEMBL25183419 0.92 FURIN (0.86) FURIN
SCHEMBL21564514 0.92 FURIN (0.85) FURIN
SCHEMBL29928241 0.92 FURIN (0.88) FURIN
SCHEMBL21550808 0.92 FURIN (0.88) FURIN
SCHEMBL21551230 0.92 FURIN (0.85) FURIN
SCHEMBL21550876 0.92 FURIN (0.92) FURIN
SCHEMBL29928073 0.92 FURIN (0.92) FURIN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3790871-B1 FURIN INHIBITORS GLAXOSMITHKLINE IP DEV LTD (GB) 2024-01-24 — — EP claimed
EP-4125897-A1 FURIN INHIBITORS FOR TREATING CORONAVIRUS INFECTIONS BP Asset V, Inc. (US) 2023-02-08 — — EP claimed
EP-4058021-A1 SMALL MOLECULE FURIN INHIBITORS FOR TREATING INFECTIOUS DISEASES BP Asset V, Inc. (US) 2022-09-21 — — EP claimed
US-20230149401-A1 FURIN INHIBITORS FOR TREATING CORONAVIRUS INFECTIONS BP ASSET V, INC. (US) 2023-05-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230149401-A1 FURIN INHIBITORS FOR TREATING CORONAVIRUS INFECTIONS FURIN, ACE, ACE2 FURIN 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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