Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 20/20 | 0.72 |
| ▸ | KDR | P35968 | 11/20 | 0.72 |
| ▸ | INSR | P06213 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4989266 | 1.00 | AXL (0.72) | AXLKDRINSR | |
| SCHEMBL4388461 | 1.00 | AXL (0.72) | AXLKDRINSR | |
| SCHEMBL4373821 | 1.00 | AXL (0.72) | AXLKDRINSR | |
| SCHEMBL4229931 | 0.94 | AXL (0.82) | AXLKDRINSR | |
| SCHEMBL4229929 | 0.94 | AXL (0.82) | AXLKDRINSR | |
| SCHEMBL4238057 | 0.94 | AXL (0.82) | AXLKDRINSR | |
| SCHEMBL4238060 | 0.94 | AXL (0.82) | AXLKDRINSR | |
| SCHEMBL4238194 | 0.94 | AXL (0.82) | AXLKDRINSR | |
| SCHEMBL4995402 | 0.94 | AXL (0.82) | AXLKDRINSR | |
| SCHEMBL4240621 | 0.90 | AXL (0.75) | AXLKDRINSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110551105-B | Substituted triazoles useful as AXL inhibitors | 里格尔制药公司 | 2022-10-18 | — | — | CN | disclosed |