Z-Astringin

Z-Astringin

SCHEMBL29928846

OC[C@H]1O[C@@H](Oc2cc(O)cc(/C=C\c3ccc(O)c(O)c3)c2)[C@H](O)[C@@H](O)[C@@H]1O

nearest known ligand 0.81

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.81
PTGS2 P35354 2/20 0.81
GAA P10253 2/20 0.81
KDM4E B2RXH2 2/20 0.81
MAPT P10636 2/20 0.81
G6PD P11413 1/20 0.81
MAPK1 P28482 1/20 0.81
ADRA1A P35348 1/20 0.81
CDK5 Q00535 1/20 0.63
CDK5R1 Q15078 1/20 0.63
PTGS1 P23219 1/20 0.59
TDP1 Q9NUW8 2/20 0.58
TYR P14679 2/20 0.56
AKR1B1 P15121 1/20 0.54
DPP4 P27487 1/20 0.54
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
HSD17B10 Q99714 1/20 0.53
ALDH1A1 P00352 1/20 0.53
RECQL P46063 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Z-Astringin SCHEMBL4255439 1.00 POLB (0.81) POLBPTGS2GAAKDM4EMAPT
Z-Astringin SCHEMBL4764496 1.00 POLB (0.81) POLBPTGS2GAAKDM4EMAPT
Z-Astringin SCHEMBL29428101 1.00 POLB (0.81) POLBPTGS2GAAKDM4EMAPT
Z-Astringin SCHEMBL501245 1.00 POLB (0.81) POLBPTGS2GAAKDM4EMAPT
Piceid SCHEMBL16419687 0.90 POLB (1.00) POLBPTGS2GAAKDM4EMAPT
Piceid SCHEMBL13252338 0.90 POLB (1.00) POLBPTGS2GAAKDM4EMAPT
Piceid SCHEMBL10182561 0.90 POLB (1.00) POLBPTGS2GAAKDM4EMAPT
SCHEMBL22522066 0.90 POLB (0.91) POLBPTGS2GAAKDM4EMAPT
Piceid SCHEMBL22111468 0.90 POLB (1.00) POLBPTGS2GAAKDM4EMAPT
Piceid SCHEMBL10148943 0.90 POLB (1.00) POLBPTGS2GAAKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250089709-A1 CALCIUM PHOSPHATE NANOPARTICLES LOADED WITH JASMONATE TO INDUCE EFFICIENT PLANT DEFENCE RESPONSES UNIVERSIDAD DE GRANADA (ES) 2025-03-20 US disclosed
WO-2024249314-A1 PRENYLTRANSFERASES FOR PRENYLATING STILBENES GINKGO BIOWORKS, INC. (US) 2024-12-05 WO disclosed
EP-4373275-A1 CALCIUM PHOSPHATE NANOPARTICLES LOADED WITH JASMONATE TO INDUCE EFFICIENT PLANT DEFENCE RESPONSES Universidad de Granada (ES) 2024-05-29 EP disclosed
WO-2023001952-A1 CALCIUM PHOSPHATE NANOPARTICLES LOADED WITH JASMONATE TO INDUCE EFFICIENT PLANT DEFENCE RESPONSES UNIVERSIDAD DE GRANADA (ES) 2023-01-26 WO disclosed
US-20220386640-A1 HIGH PROTEIN, MICELLAR CASEIN-CONTAINING NUTRITIONAL LIQUIDS ENRICHED WITH POLYPHENOLS AND METHOD OF PRODUCTION ARLA FOODS AMBA (DK) 2022-12-08 US disclosed
EP-4057832-A1 HIGH PROTEIN, MICELLAR CASEIN-CONTAINING NUTRITIONAL LIQUIDS ENRICHED WITH POLYPHENOLS AND METHOD OF PRODUCTION Arla Foods amba (DK) 2022-09-21 EP disclosed