Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 8/20 | 1.00 |
| ▸ | BACE1 | P56817 | 14/20 | 0.78 |
| ▸ | LTA4H | P09960 | 2/20 | 0.51 |
| ▸ | INSR | P06213 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3961282 | 1.00 | AXL (1.00) | AXLBACE1LTA4HINSR | |
| SCHEMBL4993710 | 0.88 | BACE1 (1.00) | AXLBACE1INSR | |
| SCHEMBL3956661 | 0.85 | BACE1 (1.00) | AXLBACE1LTA4HINSR | |
| SCHEMBL29929122 | 0.85 | BACE1 (1.00) | AXLBACE1LTA4HINSR | |
| SCHEMBL4993732 | 0.82 | BACE1 (1.00) | AXLBACE1INSR | |
| SCHEMBL12780837 | 0.76 | BACE1 (0.67) | AXLBACE1 | |
| SCHEMBL12780841 | 0.72 | KIT (0.62) | AXLBACE1 | |
| SCHEMBL12780920 | 0.72 | BACE1 (0.57) | AXLBACE1 | |
| SCHEMBL4986337 | 0.72 | BACE1 (1.00) | AXLBACE1INSR | |
| SCHEMBL4256872 | 0.72 | BACE1 (1.00) | AXLBACE1INSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110551105-B | Substituted triazoles useful as AXL inhibitors | 里格尔制药公司 | 2022-10-18 | — | — | CN | disclosed |