Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 2/20 | 1.00 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.60 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.60 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.60 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.53 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL227231 | 1.00 | P4HTM (1.00) | P4HTMNR4A2NR4A1NR4A3SRD5A2 | |
| SCHEMBL23488365 | 0.87 | P4HTM (0.77) | P4HTMNR4A2NR4A1NR4A3SRD5A2 | |
| SCHEMBL2186639 | 0.87 | P4HTM (0.77) | P4HTMNR4A2NR4A1NR4A3SRD5A2 | |
| SCHEMBL19405836 | 0.86 | P4HTM (0.74) | P4HTMNR4A2NR4A1NR4A3SRD5A2 | |
| SCHEMBL30222045 | 0.86 | P4HTM (0.75) | P4HTMPLA2G4BFFAR1ALKBH1 | |
| SCHEMBL3504363 | 0.86 | P4HTM (0.75) | P4HTMNR4A2MAOBPARP10CYP4F2 | |
| SCHEMBL20819400 | 0.84 | P4HTM (0.73) | P4HTMNR4A2NR4A1NR4A3SRD5A2 | |
| SCHEMBL21588085 | 0.84 | P4HTM (0.73) | P4HTMNR4A2NR4A1NR4A3SRD5A2 | |
| SCHEMBL20819382 | 0.84 | P4HTM (0.73) | P4HTMNR4A2NR4A1NR4A3SRD5A2 | |
| SCHEMBL11383635 | 0.84 | P4HTM (0.73) | P4HTMNR4A2NR4A1NR4A3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112279888-B | Polypeptide inhibitor of APC/Asef interaction and application thereof | 上海交通大学医学院 | 2022-09-13 | — | — | CN | disclosed |