Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 8/20 | 1.00 |
| ▸ | SLC5A1 | P13866 | 2/20 | 1.00 |
| ▸ | SLC5A2 | P31639 | 2/20 | 1.00 |
| ▸ | CACNA1G | O43497 | 2/20 | 1.00 |
| ▸ | CACNA1H | O95180 | 2/20 | 1.00 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 1.00 |
| ▸ | ESR1 | P03372 | 4/20 | 0.84 |
| ▸ | ACHE | P22303 | 2/20 | 0.84 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.84 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.84 |
| ▸ | BCHE | P06276 | 1/20 | 0.84 |
| ▸ | MAOA | P21397 | 2/20 | 0.65 |
| ▸ | MAOB | P27338 | 1/20 | 0.65 |
| ▸ | IDO1 | P14902 | 2/20 | 0.61 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.55 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.55 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.55 |
| ▸ | PDE5A | O76074 | 1/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sophoraflavanone G SCHEMBL17626648 | 1.00 | BACE1 (1.00) | BACE1SLC5A1SLC5A2CACNA1GCACNA1H | |
| Sophoraflavanone G SCHEMBL10307524 | 1.00 | BACE1 (1.00) | BACE1SLC5A1SLC5A2CACNA1GCACNA1H | |
| Sophoraflavanone G SCHEMBL29776828 | 1.00 | BACE1 (1.00) | BACE1SLC5A1SLC5A2CACNA1GCACNA1H | |
| Sophoraflavanone G SCHEMBL29929166 | 1.00 | BACE1 (1.00) | BACE1SLC5A1SLC5A2CACNA1GCACNA1H | |
| Sophoraflavanone G SCHEMBL904617 | 1.00 | BACE1 (1.00) | BACE1SLC5A1SLC5A2CACNA1GCACNA1H | |
| Sophoraflavanone G SCHEMBL15090973 | 1.00 | BACE1 (1.00) | BACE1SLC5A1SLC5A2CACNA1GCACNA1H | |
| Sophoraflavanone G SCHEMBL2228023 | 1.00 | BACE1 (1.00) | BACE1SLC5A1SLC5A2CACNA1GCACNA1H | |
| SCHEMBL10307527 | 0.93 | BACE1 (0.87) | BACE1SLC5A1SLC5A2CACNA1GCACNA1H | |
| SCHEMBL29624625 | 0.92 | BACE1 (0.85) | BACE1SLC5A1SLC5A2CACNA1GCACNA1H | |
| Kurarinone SCHEMBL904627 | 0.92 | BACE1 (1.00) | BACE1SLC5A1SLC5A2CACNA1GCACNA1H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064318-A1 | BIPHASIC COMPOSITIONS COMPRISING ONE OR BOTH OF CARBONATE AND PHOSPHATE | Natural Extraction Systems, LLC (US) | 2023-04-20 | — | — | WO | claimed |
| WO-2022182527-A1 | COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS | Natural Extraction Systems, LLC (US) | 2022-09-01 | — | — | WO | claimed |
| WO-2023064318-A1 | BIPHASIC COMPOSITIONS COMPRISING ONE OR BOTH OF CARBONATE AND PHOSPHATE | Natural Extraction Systems, LLC (US) | 2023-04-20 | — | — | WO | disclosed |