Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 13/20 | 0.70 |
| ▸ | INSR | P06213 | 10/20 | 0.70 |
| ▸ | ATM | Q13315 | 3/20 | 0.60 |
| ▸ | KDR | P35968 | 3/20 | 0.60 |
| ▸ | BACE1 | P56817 | 7/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4992512 | 1.00 | AXL (0.70) | AXLINSRATMKDRBACE1 | |
| SCHEMBL4986553 | 0.93 | AXL (0.80) | AXLINSRATMKDRBACE1 | |
| SCHEMBL4237828 | 0.83 | AXL (1.00) | AXLINSRATMKDRBACE1 | |
| SCHEMBL29928453 | 0.83 | AXL (0.75) | AXLINSRBACE1 | |
| SCHEMBL4992416 | 0.83 | AXL (0.75) | AXLINSRBACE1 | |
| SCHEMBL4235789 | 0.81 | BACE1 (0.66) | AXLINSRBACE1 | |
| SCHEMBL29928116 | 0.81 | BACE1 (0.66) | AXLINSRBACE1 | |
| SCHEMBL4993107 | 0.80 | AXL (1.00) | AXLINSRBACE1 | |
| SCHEMBL4986245 | 0.80 | AXL (1.00) | AXLINSRBACE1 | |
| SCHEMBL4997147 | 0.78 | AXL (0.77) | AXLINSRATMKDRBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110551105-B | Substituted triazoles useful as AXL inhibitors | 里格尔制药公司 | 2022-10-18 | — | — | CN | disclosed |