SCHEMBL29929835

SCHEMBL29929835

S=C(NCCCc1cnc[nH]1)NCCCN(Cc1ccc(Cl)c(Cl)c1)c1ccc(Br)cn1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GBA1 P04062 13/20 1.00
SSTR2 P30874 9/20 1.00
SSTR4 P31391 9/20 1.00
MEN1 O00255 1/20 1.00
ALDH1A1 P00352 1/20 1.00
CHRM5 P08912 1/20 1.00
ADRA2A P08913 1/20 1.00
MAPT P10636 1/20 1.00
CHRM1 P11229 1/20 1.00
ALOX12 P18054 1/20 1.00
ADRA2B P18089 1/20 1.00
ADRA2C P18825 1/20 1.00
FPR1 P21462 1/20 1.00
DRD1 P21728 1/20 1.00
DRD5 P21918 1/20 1.00
SLC6A2 P23975 1/20 1.00
ADRA1D P25100 1/20 1.00
HTR1B P28222 1/20 1.00
HTR2A P28223 1/20 1.00
HTR2C P28335 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30248346 0.92 GBA1 (1.00) GBA1SSTR2SSTR4MEN1ALDH1A1
SCHEMBL6035414 0.86 SSTR4 (0.75) GBA1SSTR2SSTR4MEN1ALDH1A1
SCHEMBL8180083 0.86 SSTR4 (0.75) GBA1SSTR2SSTR4MEN1ALDH1A1
SCHEMBL7424609 0.83 SSTR4 (1.00) GBA1SSTR2SSTR4MEN1ALDH1A1
SCHEMBL8180168 0.83 SSTR4 (0.75) GBA1SSTR2SSTR4MEN1ALDH1A1
SCHEMBL7421644 0.83 SSTR4 (0.75) GBA1SSTR2SSTR4MEN1ALDH1A1
SCHEMBL7426592 0.83 SSTR4 (0.76) GBA1SSTR2SSTR4MEN1ALDH1A1
SCHEMBL7418623 0.83 SSTR4 (0.76) GBA1SSTR2SSTR4MEN1ALDH1A1
SCHEMBL7420602 0.82 SSTR4 (0.75) GBA1SSTR2SSTR4MEN1ALDH1A1
SCHEMBL8178889 0.82 SSTR4 (0.75) GBA1SSTR2SSTR4MEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250154219-A1 PEPTIDE ANALOGS ADEPTHERA LLC 2025-05-15 US disclosed
US-12110318-B2 Peptide analogs ADEPTHERA LLC (US) 2024-10-08 US disclosed
US-20220324935-A1 PEPTIDE ANALOGS ADEPTHERA LLC 2022-10-13 US disclosed
US-11390657-B2 Peptide analogs ADEPTHERA LLC (US) 2022-07-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12110318-B2 Peptide analogs RAMP1, RAMP3, RAMP2 GBA1 3533/4885SSTR2 106/4885SSTR4 83/4885
US-20220324935-A1 PEPTIDE ANALOGS RAMP1, RAMP2, RAMP3 GBA1 3337/4885SSTR2 145/4885SSTR4 126/4885
US-20250154219-A1 PEPTIDE ANALOGS RAMP1, RAMP2, RAMP3 GBA1 3337/4885SSTR2 145/4885SSTR4 126/4885
US-11390657-B2 Peptide analogs RAMP1, RAMP3, RAMP2 GBA1 3533/4885SSTR2 106/4885SSTR4 83/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.