SCHEMBL29930244

SCHEMBL29930244

CC(C)C[C@H](NC(=O)[C@@H]1CCC(=O)N1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ NTSR2 O95665 9/20 0.56
▸ NPY4R P50391 2/20 0.48
▸ NPY1R P25929 1/20 0.48
▸ NPY2R P49146 1/20 0.48
▸ NMUR2 Q9GZQ4 2/20 0.47
▸ HRAS P01112 1/20 0.47
▸ KRAS P01116 1/20 0.47
▸ SOS1 Q07889 1/20 0.47
▸ SRC P12931 1/20 0.47
▸ NTSR1 P30989 2/20 0.45
▸ NMUR1 Q9HB89 1/20 0.45
▸ BECN1 Q14457 1/20 0.45
▸ TFPI P10646 1/20 0.45
▸ KDM1A O60341 1/20 0.44
▸ HCRTR1 O43613 1/20 0.44
▸ HCRTR2 O43614 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19682181 0.91 NMUR2 (0.52) NTSR2NPY4RNPY1RNPY2RNMUR2
SCHEMBL30446151 0.88 NMUR2 (0.67) NTSR2NPY1RNMUR2NTSR1NMUR1
SCHEMBL38650581 0.86 KDM1A (0.62) NPY4RNPY1RNPY2RNMUR2NMUR1
SCHEMBL9652970 0.82 NTSR2 (0.57) NTSR2NPY4RNPY1RNPY2RSRC
SCHEMBL31430950 0.82 NPY4R (0.54) NTSR2NPY4RNPY1RNPY2RNMUR2
SCHEMBL30512662 0.82 NPY4R (0.62) NPY4RNPY1RNPY2R
SCHEMBL10938992 0.82 KDM1A (0.49) NTSR2NPY4RNPY1RNPY2RHRAS
SCHEMBL30483715 0.81 NTSR2 (0.43) NTSR2SRC
Glaspimod SCHEMBL609834 0.81 FOLH1 (0.48) —
SCHEMBL30717622 0.80 NMUR2 (0.50) NTSR2NPY4RNPY1RNPY2RNMUR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250154219-A1 PEPTIDE ANALOGS ADEPTHERA LLC 2025-05-15 — — US disclosed
US-12110318-B2 Peptide analogs ADEPTHERA LLC (US) 2024-10-08 — — US disclosed
US-20220324935-A1 PEPTIDE ANALOGS ADEPTHERA LLC 2022-10-13 — — US disclosed
US-11390657-B2 Peptide analogs ADEPTHERA LLC (US) 2022-07-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12110318-B2 Peptide analogs RAMP1, RAMP3, RAMP2 NTSR2 25/4885NPY4R 182/4885NPY1R 119/4885
US-20220324935-A1 PEPTIDE ANALOGS RAMP1, RAMP2, RAMP3 NTSR2 44/4885NPY4R 255/4885NPY1R 115/4885
US-20250154219-A1 PEPTIDE ANALOGS RAMP1, RAMP2, RAMP3 NTSR2 44/4885NPY4R 255/4885NPY1R 115/4885
US-11390657-B2 Peptide analogs RAMP1, RAMP3, RAMP2 NTSR2 25/4885NPY4R 182/4885NPY1R 119/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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