Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 8/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | MAPK3 | P27361 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23901633 | 1.00 | PTPN11 (0.39) | PTPN11KCNH2MAPK3MAPK1FAAH | |
| SCHEMBL29734754 | 0.99 | PTPN11 (0.39) | PTPN11KCNH2MAPK3MAPK1 | |
| SCHEMBL26920918 | 0.91 | PTPN11 (0.35) | PTPN11KCNH2MAPK3MAPK1 | |
| SCHEMBL18320517 | 0.79 | PTPN11 (0.36) | PTPN11KCNH2MAPK3MAPK1 | |
| SCHEMBL31184258 | 0.79 | PTPN11 (0.36) | PTPN11KCNH2MAPK3MAPK1 | |
| SCHEMBL18328573 | 0.76 | PTPN11 (0.36) | PTPN11KCNH2 | |
| SCHEMBL29595742 | 0.76 | PTPN11 (0.50) | PTPN11KCNH2MAPK3MAPK1 | |
| SCHEMBL18319495 | 0.76 | PTPN11 (0.50) | PTPN11KCNH2MAPK3MAPK1 | |
| SCHEMBL23901635 | 0.76 | PTPN11 (0.46) | PTPN11KCNH2 | |
| SCHEMBL23901702 | 0.73 | PTPN11 (0.53) | PTPN11KCNH2MAPK3MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113493440-B | Salt of nitrogen-containing heteroaromatic derivative and crystal form thereof | 上海翰森生物医药科技有限公司 | 2024-08-23 | — | — | CN | disclosed |
| CN-115052866-B | Crystal form of nitrogen-containing heteroaromatic derivative free alkali | 上海翰森生物医药科技有限公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-115353509-B | Nitrogen-containing heteroaromatic derivative regulator, preparation method and application thereof | 江苏豪森药业集团有限公司 | 2024-04-12 | — | — | CN | disclosed |
| CN-115353509-A | Aza-containing aromatic derivative regulator, preparation method and application thereof | 江苏豪森药业集团有限公司 | 2022-11-18 | — | — | CN | disclosed |
| CN-111295374-B | Aza-containing aromatic derivative regulator, preparation method and application thereof | 江苏豪森药业集团有限公司 | 2022-11-04 | — | — | CN | disclosed |
| CN-115052866-A | Crystal form of free base of nitrogen-containing heteroaromatic derivative | 上海翰森生物医药科技有限公司 | 2022-09-13 | — | — | CN | disclosed |