Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 10/20 | 0.80 |
| ▸ | CHRM4 | P08173 | 7/20 | 0.80 |
| ▸ | CHRM3 | P20309 | 8/20 | 0.76 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.48 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.48 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.48 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29930663 | 0.89 | CHRM2 (1.00) | CHRM2CHRM4CHRM3CHRM1KMT2A | |
| SCHEMBL29930254 | 0.83 | CHRM2 (1.00) | CHRM2CHRM4CHRM3CHRM1KMT2A | |
| SCHEMBL28643422 | 0.83 | CHRM2 (1.00) | CHRM2CHRM4CHRM3CHRM1KMT2A | |
| SCHEMBL28643439 | 0.81 | CHRM2 (1.00) | CHRM2CHRM4CHRM3CHRM1KMT2A | |
| SCHEMBL29930459 | 0.81 | CHRM2 (1.00) | CHRM2CHRM4CHRM3CHRM1KMT2A | |
| SCHEMBL29930872 | 0.80 | CHRM2 (0.63) | CHRM2CHRM4CHRM3CHRM1KMT2A | |
| SCHEMBL28646672 | 0.78 | CHRM2 (1.00) | CHRM2CHRM4CHRM3CHRM1KMT2A | |
| SCHEMBL29930613 | 0.78 | CHRM2 (1.00) | CHRM2CHRM4CHRM3CHRM1KMT2A | |
| SCHEMBL9979483 | 0.77 | CHRM2 (0.54) | CHRM2CHRM4CHRM3CHRM1KMT2A | |
| SCHEMBL28647927 | 0.77 | CHRM2 (1.00) | CHRM2CHRM4CHRM3CHRM1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113527172-B | M2 acetylcholine receptor antagonists and uses thereof | 上海交通大学医学院附属仁济医院 | 2022-10-25 | — | — | CN | disclosed |