Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.82 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.82 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.82 |
| ▸ | POLB | P06746 | 1/20 | 0.82 |
| ▸ | MAPT | P10636 | 1/20 | 0.82 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.82 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.82 |
| ▸ | CHRM2 | P08172 | 17/20 | 0.72 |
| ▸ | CHRM4 | P08173 | 17/20 | 0.72 |
| ▸ | CHRM1 | P11229 | 17/20 | 0.72 |
| ▸ | CHRM3 | P20309 | 16/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1091210 | 1.00 | MEN1 (0.82) | MEN1KMT2AKDM4EPOLBMAPT | |
| Hydrochloric Acid SCHEMBL5797212 | 0.98 | MEN1 (0.80) | MEN1KMT2AKDM4EPOLBMAPT | |
| SCHEMBL30674384 | 0.91 | MEN1 (0.68) | MEN1KMT2AKDM4EPOLBMAPT | |
| SCHEMBL31427175 | 0.90 | MEN1 (1.00) | MEN1KMT2AKDM4EPOLBMAPT | |
| SCHEMBL7824829 | 0.90 | MEN1 (1.00) | MEN1KMT2AKDM4EPOLBMAPT | |
| SCHEMBL1105634 | 0.88 | MEN1 (0.65) | MEN1KMT2AKDM4EPOLBMAPT | |
| SCHEMBL8343391 | 0.88 | CHRM2 (0.68) | MEN1KMT2AKDM4EPOLBMAPT | |
| SCHEMBL31093163 | 0.87 | CHRM2 (0.67) | MEN1KMT2AKDM4EPOLBMAPT | |
| SCHEMBL1102038 | 0.84 | CHRM2 (0.70) | MEN1KMT2AKDM4EPOLBMAPT | |
| SCHEMBL28643871 | 0.84 | CHRM2 (1.00) | CHRM2CHRM4CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113527172-B | M2 acetylcholine receptor antagonists and uses thereof | 上海交通大学医学院附属仁济医院 | 2022-10-25 | — | — | CN | disclosed |