Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL71938 | 1.00 | HSD17B10 (0.60) | HSD17B10ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL29930704 | 0.87 | HSD17B10 (0.62) | HSD17B10ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL23611759 | 0.87 | HSD17B10 (0.62) | HSD17B10ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL24025727 | 0.84 | BRD4 (0.49) | HSD17B10MEN1KMT2AMAPTPOLB | |
| SCHEMBL1528145 | 0.84 | KMT2A (0.55) | HSD17B10ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL8695064 | 0.84 | MEN1 (0.49) | HSD17B10ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL13779277 | 0.83 | HSD17B10 (0.58) | HSD17B10ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL1528634 | 0.83 | MAPT (0.50) | HSD17B10ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL9071981 | 0.83 | HSD17B10 (0.69) | HSD17B10ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL14438952 | 0.82 | HSD17B10 (0.53) | HSD17B10ALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115210229-A | Polycyclic amides as UBE2K modulators for the treatment of cancer | 博格有限责任公司 | 2022-10-18 | — | — | CN | disclosed |