Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 16/20 | 0.51 |
| ▸ | NPY1R | P25929 | 10/20 | 0.51 |
| ▸ | NPY5R | Q15761 | 9/20 | 0.51 |
| ▸ | NPY2R | P49146 | 6/20 | 0.51 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29876897 | 0.97 | NPY4R (0.51) | NPY4RNPY1RNPY5RNPY2RNTSR2 | |
| SCHEMBL29859761 | 0.93 | MAPK8 (0.47) | NPY4RNPY1RNPY5RNPY2RKDM1A | |
| SCHEMBL7174450 | 0.93 | CTSC (0.49) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL29387797 | 0.93 | CTSC (0.49) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL7174455 | 0.93 | CTSC (0.49) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL29895402 | 0.93 | NPY4R (0.47) | NPY4RNPY1RNPY5RNPY2RKDM1A | |
| SCHEMBL7643912 | 0.93 | KDM1A (0.49) | NPY4RNPY1RNPY5RNPY2RKDM1A | |
| SCHEMBL7643925 | 0.93 | KDM1A (0.49) | NPY4RNPY1RNPY5RNPY2RKDM1A | |
| SCHEMBL30942554 | 0.92 | NPY4R (0.61) | NPY4RNPY1RNPY5RNPY2RNTSR2 | |
| SCHEMBL30540727 | 0.91 | NPY4R (0.47) | NPY4RNPY1RNPY5RNPY2RNTSR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11648293-B2 | Compositions and methods for treating cancer | BIOKINE THERAPEUTICS LTD. (IL) | 2023-05-16 | — | — | US | disclosed |
| US-20220288155-A1 | CXCR4 INHIBITOR FOR THE TREATMENT OF ACUTE RESPIRATORY DISTRESS SYNDROME AND VIRAL INFECTIONS | BIOLINERX LTD. (IL) | 2022-09-15 | — | — | US | disclosed |