Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | MMP1 | P03956 | 1/20 | 0.56 |
| ▸ | MMP2 | P08253 | 1/20 | 0.56 |
| ▸ | MMP9 | P14780 | 1/20 | 0.56 |
| ▸ | MMP8 | P22894 | 1/20 | 0.56 |
| ▸ | MMP13 | P45452 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20139557 | 1.00 | CA1 (0.56) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL968537 | 1.00 | CA1 (0.56) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL968534 | 1.00 | CA1 (0.56) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL23779402 | 0.83 | CA1 (0.59) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL14990815 | 0.83 | CA1 (0.59) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL14990813 | 0.83 | CA1 (0.59) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL20139873 | 0.83 | CA1 (0.47) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL29932987 | 0.83 | CA1 (0.47) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL20139870 | 0.83 | CA1 (0.47) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL31220337 | 0.83 | CA1 (0.52) | CA1CA2MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110099684-B | Compounds and methods for modulating interleukin-2-inducible T cell kinase | 科尔沃斯制药股份有限公司 | 2022-11-11 | — | — | CN | disclosed |