Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | MEN1 | O00255 | 6/20 | 0.55 |
| ▸ | GAA | P10253 | 6/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | APP | P05067 | 6/20 | 0.50 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.50 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12396131 | 1.00 | MAPT (0.55) | MAPTKMT2AALDH1A1MEN1GAA | |
| SCHEMBL4664740 | 0.79 | MAPT (0.64) | MAPTKMT2AALDH1A1MEN1GAA | |
| SCHEMBL3407787 | 0.76 | MAPT (0.60) | MAPTKMT2AALDH1A1MEN1GAA | |
| SCHEMBL29851934 | 0.76 | MAPT (0.60) | MAPTKMT2AALDH1A1MEN1GAA | |
| SCHEMBL6951600 | 0.76 | MAPT (0.60) | MAPTKMT2AALDH1A1MEN1GAA | |
| SCHEMBL3533968 | 0.76 | KMT2A (0.60) | MAPTKMT2AALDH1A1MEN1GAA | |
| SCHEMBL4661622 | 0.76 | MAPT (0.60) | MAPTKMT2AALDH1A1MEN1GAA | |
| SCHEMBL14759038 | 0.76 | MAPT (0.60) | MAPTKMT2AALDH1A1MEN1GAA | |
| SCHEMBL10597685 | 0.76 | MAPT (0.60) | MAPTKMT2AALDH1A1MEN1GAA | |
| SCHEMBL30590658 | 0.74 | MAPT (0.57) | MAPTKMT2AALDH1A1MEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115109073-A | Crystalline tylorravone | 南京中瑞药业有限公司 | 2022-09-27 | — | — | CN | disclosed |