Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 6/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 8/20 | 0.59 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.59 |
| ▸ | APLNR | P35414 | 1/20 | 0.59 |
| ▸ | CCR6 | P51684 | 1/20 | 0.59 |
| ▸ | F3 | P13726 | 3/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | USP7 | Q93009 | 1/20 | 0.54 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.54 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | IKBKB | O14920 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13559837 | 0.95 | TOP1 (0.66) | TOP1PTPN1CXCR5APLNRCCR6 | |
| SCHEMBL13559854 | 0.94 | PTPN1 (0.57) | TOP1PTPN1CXCR5APLNRCCR6 | |
| SCHEMBL13559849 | 0.94 | PTPN1 (0.57) | TOP1PTPN1CXCR5APLNRCCR6 | |
| SCHEMBL19360128 | 0.93 | CXCR5 (0.67) | TOP1PTPN1CXCR5APLNRCCR6 | |
| SCHEMBL12944982 | 0.93 | CXCR5 (0.67) | TOP1PTPN1CXCR5APLNRCCR6 | |
| SCHEMBL29934956 | 0.93 | PTPN1 (0.68) | TOP1PTPN1CXCR5APLNRCCR6 | |
| SCHEMBL13007185 | 0.91 | TOP1 (0.57) | TOP1PTPN1CXCR5APLNRCCR6 | |
| SCHEMBL9061363 | 0.90 | TOP1 (0.58) | TOP1PTPN1CXCR5APLNRCCR6 | |
| SCHEMBL13559851 | 0.89 | PTPN1 (0.61) | TOP1PTPN1CXCR5APLNRCCR6 | |
| SCHEMBL13559850 | 0.89 | PTPN1 (0.61) | TOP1PTPN1CXCR5APLNRCCR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220291237-A1 | Gene Expression Inflammatory Age and Its Uses | Edifice Health, Inc. (US) | 2022-09-15 | — | — | US | disclosed |