SCHEMBL29934352

SCHEMBL29934352

COc1ccc([C@H]2Oc3cc(O)cc(O)c3C[C@H]2O)cc1O

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 6/20 0.74
KDM4E B2RXH2 5/20 0.74
PTGS1 P23219 5/20 0.74
GAA P10253 3/20 0.74
MEN1 O00255 3/20 0.74
KMT2A Q03164 3/20 0.74
HSD17B10 Q99714 3/20 0.74
ALDH1A1 P00352 3/20 0.74
MAPT P10636 3/20 0.74
APEX1 P27695 3/20 0.74
RECQL P46063 3/20 0.74
SNCA P37840 3/20 0.74
CYP3A4 P08684 3/20 0.74
PKM P14618 2/20 0.74
ALPL P05186 2/20 0.74
POLB P06746 2/20 0.74
PTGS2 P35354 2/20 0.74
RAD52 P43351 2/20 0.74
HPGD P15428 2/20 0.74
ALOX15 P16050 2/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL348595 1.00 BACE1 (0.74) BACE1KDM4EPTGS1GAAMEN1
SCHEMBL349872 1.00 BACE1 (0.74) BACE1KDM4EPTGS1GAAMEN1
SCHEMBL30843342 1.00 BACE1 (0.74) BACE1KDM4EPTGS1GAAMEN1
SCHEMBL348596 1.00 BACE1 (0.74) BACE1KDM4EPTGS1GAAMEN1
SCHEMBL31028352 0.94 BACE1 (0.69) BACE1KDM4EPTGS1GAAMEN1
SCHEMBL5924559 0.94 BACE1 (0.69) BACE1KDM4EPTGS1GAAMEN1
SCHEMBL862104 0.94 BACE1 (0.69) BACE1KDM4EPTGS1GAAMEN1
SCHEMBL5074728 0.94 BACE1 (0.69) BACE1KDM4EPTGS1GAAMEN1
SCHEMBL862117 0.93 BACE1 (0.63) BACE1KDM4EPTGS1GAAMEN1
3'-O-Methyl Epicatechin SCHEMBL25248714 0.91 BACE1 (0.73) BACE1KDM4EPTGS1GAAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747367-A1 NEW ENZYMES FOR THE MANUFACTURING OF 4'-O-METHYLATED PHENOLIC SUBSTANCES Symrise AG (DE) 2026-05-27 EP disclosed
CN-122055354-A Lipid compounds and related compositions and uses 波西达治疗公司 2026-05-15 CN disclosed
EP-4655410-A2 O-METHYLATION OF PHENOLIC SUBSTANCES VIA FUNGAL O-METHYLTRANSFERASE Symrise AG (DE) 2025-12-03 EP disclosed
WO-2025016533-A1 NEW ENZYMES FOR THE MANUFACTURING OF 4'-O-METHYLATED PHENOLIC SUBSTANCES SYMRISE AG (DE) 2025-01-23 WO disclosed
WO-2025017042-A1 NEW ENZYMES FOR THE MANUFACTURING OF 4'-O-METHYLATED PHENOLIC SUBSTANCES SYMRISE AG (DE) 2025-01-23 WO disclosed
CN-118546792-A Eurotium cristatum and application thereof in catalytic metabolism conversion of EGCG 湖南农业大学 2024-08-27 CN disclosed
WO-2024156359-A1 O-METHYLATION OF PHENOLIC SUBSTANCES VIA FUNGAL O-METHYLTRANSFERASE SYMRISE AG (DE) 2024-08-02 WO disclosed
WO-2024156879-A2 O-METHYLATION OF PHENOLIC SUBSTANCES VIA FUNGAL O-METHYLTRANSFERASE SYMRISE AG (DE) 2024-08-02 WO disclosed
CN-117580591-A Carbitol-polyol-active agent ternary complex, pharmaceutical composition for topical use comprising said ternary complex, method for obtaining said ternary complex and use thereof in different pathological states 盖克基金会 2024-02-20 CN disclosed
CN-115298171-A Method for producing epigallocatechin gallate conjugate 花王株式会社 2022-11-04 CN disclosed
US-20220291237-A1 Gene Expression Inflammatory Age and Its Uses Edifice Health, Inc. (US) 2022-09-15 US disclosed