Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.69 |
| ▸ | SENP1 | Q9P0U3 | 2/20 | 0.64 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.57 |
| ▸ | PDE5A | O76074 | 1/20 | 0.57 |
| ▸ | PDE9A | O76083 | 1/20 | 0.57 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.57 |
| ▸ | GYS2 | P54840 | 1/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.57 |
| ▸ | EGFR | P00533 | 1/20 | 0.56 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.55 |
| ▸ | GABRP | O00591 | 1/20 | 0.53 |
| ▸ | GABRD | O14764 | 1/20 | 0.53 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.53 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.53 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.53 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.53 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.53 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.53 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10014347 | 0.88 | PTPN1 (0.66) | PDE4DPDE5APDE9APDE1BPTPN1 | |
| SCHEMBL29649785 | 0.88 | PDE4D (0.73) | ACHESENP1PDE4DPDE5APDE9A | |
| SCHEMBL12181496 | 0.88 | PDE4D (0.73) | ACHESENP1PDE4DPDE5APDE9A | |
| SCHEMBL29649857 | 0.88 | PDE4D (0.73) | ACHESENP1PDE4DPDE5APDE9A | |
| SCHEMBL24433073 | 0.88 | PDE4D (0.73) | ACHESENP1PDE4DPDE5APDE9A | |
| SCHEMBL24433072 | 0.88 | PDE4D (0.73) | ACHESENP1PDE4DPDE5APDE9A | |
| SCHEMBL12181490 | 0.88 | PDE4D (0.73) | ACHESENP1PDE4DPDE5APDE9A | |
| SCHEMBL29934465 | 0.84 | PTPN1 (0.66) | ACHESENP1PDE4DPDE5APDE9A | |
| SCHEMBL15163880 | 0.83 | PDE4D (0.68) | ACHESENP1PDE4DPDE5APDE9A | |
| SCHEMBL15163884 | 0.83 | PDE4D (0.68) | ACHESENP1PDE4DPDE5APDE9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220291237-A1 | Gene Expression Inflammatory Age and Its Uses | Edifice Health, Inc. (US) | 2022-09-15 | — | — | US | disclosed |