Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.81 |
| ▸ | MEN1 | O00255 | 2/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.81 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.81 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.81 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.81 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.81 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.81 |
| ▸ | HTT | P42858 | 1/20 | 0.81 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.81 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.81 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.65 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.59 |
| ▸ | PGR | P06401 | 2/20 | 0.48 |
| ▸ | KIF11 | P52732 | 3/20 | 0.42 |
| ▸ | PTPRS | Q13332 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 3/20 | 0.38 |
| ▸ | CNR2 | P34972 | 3/20 | 0.38 |
| ▸ | GPR18 | Q14330 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Paxilline SCHEMBL25470663 | 0.90 | MAPT (1.00) | MAPTMEN1KMT2ACYP1A2CYP3A4 | |
| Paxilline SCHEMBL25011262 | 0.90 | MAPT (1.00) | MAPTMEN1KMT2ACYP1A2CYP3A4 | |
| Paxilline SCHEMBL361232 | 0.90 | MAPT (1.00) | MAPTMEN1KMT2ACYP1A2CYP3A4 | |
| Paxilline SCHEMBL25470668 | 0.90 | MAPT (1.00) | MAPTMEN1KMT2ACYP1A2CYP3A4 | |
| Paxilline SCHEMBL5955728 | 0.90 | MAPT (1.00) | MAPTMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL22953608 | 0.82 | MAPT (0.75) | MAPTMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL29934466 | 0.80 | MAPT (0.66) | MAPTMEN1KMT2ACYP1A2CYP3A4 | |
| Paxilline SCHEMBL20857134 | 0.79 | MAPT (0.78) | MAPTMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL13883195 | 0.77 | MAPT (0.76) | MAPTMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL25470659 | 0.76 | MAPT (0.70) | MAPTMEN1KMT2ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116024119-A | Streptomyces nigromaculatus and application thereof in prevention and control of root rot of solanaceous vegetables | 甘肃省科学院生物研究所 | 2023-04-28 | — | — | CN | disclosed |
| US-20220291237-A1 | Gene Expression Inflammatory Age and Its Uses | Edifice Health, Inc. (US) | 2022-09-15 | — | — | US | disclosed |