Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2993540 | 0.82 | TSHR (0.62) | TSHRCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL1612786 | 0.71 | KMT2A (0.69) | TSHRALDH1A1SMN1; SMN2POLBRAB9A | |
| SCHEMBL3118173 | 0.70 | SMN1; SMN2 (0.69) | ALDH1A1SMN1; SMN2NPSR1POLBRAB9A | |
| SCHEMBL2996057 | 0.70 | MEN1 (0.63) | ALDH1A1SMN1; SMN2POLBRAB9AMEN1 | |
| SCHEMBL31161040 | 0.69 | MAPT (0.47) | TSHRALDH1A1SMN1; SMN2POLBKDM4E | |
| SCHEMBL22873289 | 0.68 | PARP1 (0.44) | KDM4EMEN1KMT2AHDAC6LMNA | |
| SCHEMBL2993293 | 0.68 | KDM4E (0.55) | TSHRALDH1A1SMN1; SMN2POLBKDM4E | |
| SCHEMBL3322075 | 0.67 | KDM4E (0.68) | CYP1A2CYP2C19POLBKDM4EHDAC6 | |
| SCHEMBL1520877 | 0.66 | KDM4E (0.49) | CYP1A2ALDH1A1KDM4ELMNA | |
| SCHEMBL14397087 | 0.66 | KDM4E (0.78) | TSHRALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100189685-A1 | Antiviral Drugs for Treatment or Prevention of Dengue Infection | SIGA TECHNOLOGIES, INC. | 2010-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100189685-A1 | Antiviral Drugs for Treatment or Prevention of Dengue Infection | EIF2AK2, HAVCR2, SNRPE | TSHR 4208/4885CYP1A2 3195/4885CYP2C9 2207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.