Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 7/20 | 0.44 |
| ▸ | DRD1 | P21728 | 7/20 | 0.44 |
| ▸ | DRD5 | P21918 | 6/20 | 0.44 |
| ▸ | DRD3 | P35462 | 6/20 | 0.44 |
| ▸ | DRD4 | P21917 | 3/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1445130 | 0.87 | CYP2A6 (0.43) | CYP1A2DRD2DRD1DRD5DRD3 | |
| SCHEMBL2771201 | 0.87 | CYP2A6 (0.48) | CYP1A2DRD2DRD1DRD5DRD3 | |
| SCHEMBL1525601 | 0.83 | — | — | |
| SCHEMBL22081972 | 0.83 | CYP1A2 (0.62) | CYP1A2DRD2DRD1DRD5DRD3 | |
| SCHEMBL10534995 | 0.83 | — | — | |
| SCHEMBL109650 | 0.83 | CYP1A2 (0.62) | CYP1A2DRD2DRD1DRD5DRD3 | |
| SCHEMBL29881712 | 0.83 | — | — | |
| SCHEMBL29535100 | 0.82 | TSHR (0.62) | CYP1A2DRD2DRD1DRD5DRD3 | |
| Water SCHEMBL2528680 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL4314909 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220290159-A1 | miRNAS FOR REDUCING VENTRICLE ENLARGEMENT | St. Jude Children's Research Hpspital, Inc. (US) | 2022-09-15 | — | — | US | disclosed |