SCHEMBL29936658

SCHEMBL29936658

c1ccc2c(N3CCNCC3)ncnc2c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTK2 Q05397 1/20 0.67
HRH4 Q9H3N8 1/20 0.67
HTT P42858 2/20 0.64
LMNA P02545 3/20 0.61
SMN1; SMN2 Q16637 1/20 0.61
CYP1A2 P05177 9/20 0.60
CYP3A4 P08684 9/20 0.60
CLK4 Q9HAZ1 6/20 0.60
CYP2C19 P33261 5/20 0.60
ALDH1A1 P00352 3/20 0.60
HRH1 P35367 1/20 0.58
HRH3 Q9Y5N1 1/20 0.58
HTR2C P28335 5/20 0.58
ADRB2 P07550 1/20 0.58
NCF1 P14598 1/20 0.58
KDM4E B2RXH2 3/20 0.56
HSD17B10 Q99714 3/20 0.56
USP2 O75604 3/20 0.56
MAPT P10636 2/20 0.56
HPGD P15428 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1029331 1.00 PTK2 (0.67) PTK2HRH4HTTLMNASMN1; SMN2
Hydrochloric Acid SCHEMBL2797449 0.98 PTK2 (0.65) PTK2HRH4HTTLMNASMN1; SMN2
Hydrochloric Acid SCHEMBL30059021 0.98 PTK2 (0.65) PTK2HRH4HTTLMNASMN1; SMN2
Hydrazine SCHEMBL2797134 0.97 PTK2 (0.63) PTK2HRH4HTTLMNASMN1; SMN2
SCHEMBL5235576 0.94 PTK2 (0.60) PTK2HRH4HTTLMNASMN1; SMN2
SCHEMBL11015775 0.84 PTK2 (0.73) PTK2HRH4HTTLMNASMN1; SMN2
SCHEMBL30821993 0.83 PTK2 (0.71) PTK2HRH4HTTLMNASMN1; SMN2
SCHEMBL6569122 0.83 PTK2 (0.71) PTK2HRH4HTTLMNASMN1; SMN2
SCHEMBL2203931 0.81 PTK2 (0.69) PTK2HRH4HTTLMNASMN1; SMN2
SCHEMBL29974523 0.81 PTK2 (0.56) PTK2HRH4HTTLMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022235091-A1 NOVEL HETEROCYCLIC COMPOUND AND USE THEREOF 엠비디 주식회사 2022-11-10 WO disclosed