Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 7/20 | 0.47 |
| ▸ | CA2 | P00918 | 7/20 | 0.47 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29035981 | 0.82 | MAPT (0.47) | MAPTCES2CES1ALOX15ALDH1A1 | |
| SCHEMBL1507665 | 0.81 | CA1 (0.54) | MAPTCES2CES1ALOX15ALDH1A1 | |
| SCHEMBL6045338 | 0.76 | KCNN4 (0.55) | MAPTCES2CES1ALDH1A1CA1 | |
| SCHEMBL2316036 | 0.75 | KCNN4 (0.53) | MAPTCES2CES1ALDH1A1CA1 | |
| SCHEMBL17420611 | 0.73 | CA1 (0.50) | MAPTCES2CES1ALOX15ALDH1A1 | |
| SCHEMBL28277045 | 0.72 | MAPT (0.55) | MAPTCES2CES1ALOX15ALDH1A1 | |
| SCHEMBL30087732 | 0.72 | CA1 (0.52) | MAPTCES2CES1ALOX15ALDH1A1 | |
| SCHEMBL28637684 | 0.72 | MAPT (0.46) | MAPTCES2CES1ALOX15ALDH1A1 | |
| SCHEMBL21501142 | 0.72 | CA1 (0.48) | MAPTCES2CES1ALOX15ALDH1A1 | |
| SCHEMBL28302793 | 0.72 | MAPT (0.50) | MAPTCES2CES1ALOX15ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115093527-B | Two-dimensional covalent organic framework compound with interlayer ABC staggered stacking structure and preparation method and application thereof | 浙江工业大学 | 2023-05-23 | — | — | CN | disclosed |
| CN-115093527-A | Two-dimensional covalent organic framework compound with interlayer ABC staggered accumulation structure and preparation method and application thereof | 浙江工业大学 | 2022-09-23 | — | — | CN | disclosed |