Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.53 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | PSMB1 | P20618 | 4/20 | 0.49 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.49 |
| ▸ | PSMB2 | P49721 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | KDR | P35968 | 5/20 | 0.47 |
| ▸ | FLT3 | P36888 | 3/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | JAK1 | P23458 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | FLT1 | P17948 | 2/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21296750 | 1.00 | MCHR1 (0.53) | MCHR1LTA4HPSMB1PSMB5PSMB2 | |
| SCHEMBL29937757 | 0.88 | MCHR1 (0.54) | MCHR1LTA4HPSMB1PSMB5PSMB2 | |
| SCHEMBL21296735 | 0.88 | MCHR1 (0.54) | MCHR1LTA4HPSMB1PSMB5PSMB2 | |
| SCHEMBL29937831 | 0.85 | MCHR1 (0.55) | MCHR1LTA4HPSMB1PSMB5PSMB2 | |
| SCHEMBL21296737 | 0.83 | MCHR1 (0.55) | MCHR1LTA4HPSMB1PSMB5PSMB2 | |
| SCHEMBL21296819 | 0.82 | MCHR1 (0.54) | MCHR1LTA4HPSMB1PSMB5PSMB2 | |
| SCHEMBL21296788 | 0.82 | FLT3 (0.54) | MCHR1LTA4HPSMB1PSMB5PSMB2 | |
| SCHEMBL21296793 | 0.82 | KDR (0.54) | MCHR1LTA4HPSMB1PSMB5PSMB2 | |
| SCHEMBL21296824 | 0.82 | KDR (0.58) | MCHR1LTA4HPSMB1PSMB5PSMB2 | |
| SCHEMBL21296753 | 0.81 | MCHR1 (0.51) | MCHR1LTA4HPSMB1PSMB5PSMB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022226133-A1 | MULTIFACETED APPROACH TO NOVEL INTERLEUKIN-6 INHIBITORS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2022-10-27 | — | — | WO | disclosed |