Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 4/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.45 |
| ▸ | SCD | O00767 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20702466 | 1.00 | ADORA1 (0.45) | ADORA1ADORA2ASCDMEN1KMT2A | |
| SCHEMBL30128173 | 0.89 | ADORA2A (0.45) | ADORA1ADORA2ASCDMEN1KMT2A | |
| SCHEMBL22027655 | 0.89 | ADORA2A (0.45) | ADORA1ADORA2ASCDMEN1KMT2A | |
| SCHEMBL22027625 | 0.88 | ADORA2A (0.44) | ADORA1ADORA2ASCDMEN1KMT2A | |
| SCHEMBL20702447 | 0.88 | LRRK2 (0.40) | ADORA1ADORA2ACHRM4MAPTLRRK2 | |
| SCHEMBL30128168 | 0.87 | ADORA2A (0.46) | ADORA1ADORA2ASCDMEN1KMT2A | |
| SCHEMBL20702422 | 0.87 | ADORA2A (0.46) | ADORA1ADORA2ASCDMEN1KMT2A | |
| SCHEMBL31256925 | 0.87 | ADORA1 (0.44) | ADORA1ADORA2ASCDMEN1KMT2A | |
| SCHEMBL22027632 | 0.87 | CCNE1 (0.42) | ADORA1ADORA2AMEN1KMT2AMAPT | |
| SCHEMBL30128068 | 0.87 | CCNE1 (0.42) | ADORA1ADORA2AMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110997681-B | Thiazolopyridine derivatives as adenosine receptor antagonists | 默克专利股份公司 | 2022-11-15 | — | — | CN | disclosed |