Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL29940225

O=C(O)C(F)(F)F.O=C(O)c1ccc(NCC2CCN(Cc3cc(C(F)(F)F)ccc3C3CC3)CC2)cc1

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SSTR5 P35346 4/20 0.54
LIPC P11150 1/20 0.42
LIPG Q9Y5X9 1/20 0.42
KCNH2 Q12809 1/20 0.42
CACNA1I Q9P0X4 1/20 0.42
LTA4H P09960 1/20 0.41
HIF1A Q16665 1/20 0.41
EPAS1 Q99814 1/20 0.41
SCN1A P35498 1/20 0.40
SCN4A P35499 1/20 0.40
SCN7A Q01118 1/20 0.40
SCN5A Q14524 1/20 0.40
SCN9A Q15858 1/20 0.40
SCN2A Q99250 1/20 0.40
SCN3A Q9NY46 1/20 0.40
SCN8A Q9UQD0 1/20 0.40
CCR2 P41597 1/20 0.40
CHRM4 P08173 1/20 0.40
FFAR1 O14842 2/20 0.39
CRHR1 P34998 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29940176 0.77 SSTR5 (0.47) SSTR5KCNH2CACNA1ISCN1ASCN4A
Trifluoroacetic Acid SCHEMBL29939617 0.76 SSTR5 (0.58) SSTR5KCNH2SCN9AFFAR1MRGPRX4
Trifluoroacetic Acid SCHEMBL29940172 0.72 KMT2A (0.45) LIPCLIPGCHRM4
SCHEMBL12182451 0.70 SSTR5 (0.64) SSTR5
SCHEMBL18243858 0.70 SCN9A (0.63) SSTR5SCN1ASCN4ASCN7ASCN5A
Trifluoroacetic Acid SCHEMBL31225138 0.70 FFAR1 (0.57) FFAR1
SCHEMBL15538494 0.69 SSTR5 (0.53) SSTR5KCNH2CACNA1ILTA4HSCN5A
SCHEMBL25315694 0.69 SSTR5 (0.65) SSTR5KCNH2
SCHEMBL15540337 0.68 SSTR5 (0.52) SSTR5KCNH2CACNA1ILTA4HSCN5A
SCHEMBL17371276 0.68 KMT2A (0.49) SSTR5LIPCLIPGLTA4HCRHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115215787-A Somatostatin receptor 5 antagonists and uses thereof 中国科学院上海药物研究所 2022-10-21 CN disclosed