SCHEMBL29940236

SCHEMBL29940236

CCOc1ccc(C2CC2)c(CN2CCC(F)(COc3ccc(C(=O)O)cc3)CC2)c1

nearest known ligand 0.59

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SSTR5 P35346 20/20 0.59
KCNH2 Q12809 2/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL29939617 0.84 SSTR5 (0.58) SSTR5KCNH2
SCHEMBL29939719 0.81 SSTR5 (0.72) SSTR5KCNH2
SCHEMBL29940202 0.77 SSTR5 (0.71) SSTR5KCNH2
SCHEMBL29940229 0.75 SSTR5 (1.00) SSTR5KCNH2
SCHEMBL25317822 0.74 SSTR5 (0.53) SSTR5KCNH2
Trifluoroacetic Acid SCHEMBL29940329 0.74 SSTR5 (0.69) SSTR5KCNH2
Trifluoroacetic Acid SCHEMBL29940320 0.71 SSTR5 (0.79) SSTR5KCNH2
SCHEMBL28336722 0.70 SCN9A (0.54) SSTR5KCNH2
Trifluoroacetic Acid SCHEMBL31225201 0.69 SSTR5 (0.46) SSTR5KCNH2
SCHEMBL25311447 0.69 SSTR5 (0.51) SSTR5KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115215787-A Somatostatin receptor 5 antagonists and uses thereof 中国科学院上海药物研究所 2022-10-21 CN disclosed