Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 8/20 | 0.60 |
| ▸ | CDK8 | P49336 | 8/20 | 0.60 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.54 |
| ▸ | IKBKB | O14920 | 2/20 | 0.52 |
| ▸ | CHUK | O15111 | 2/20 | 0.52 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | BRAF | P15056 | 1/20 | 0.45 |
| ▸ | CDK19 | Q9BWU1 | 2/20 | 0.45 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.42 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6997464 | 0.81 | PI4K2A (0.55) | PI4K2AIKBKBCHUKAR | |
| SCHEMBL28264516 | 0.81 | PI4K2A (0.55) | PI4K2AIKBKBCHUKAR | |
| SCHEMBL29740440 | 0.76 | AR (0.54) | CCNCCDK8ARBRAFCDK19 | |
| SCHEMBL3462850 | 0.76 | CCNC (0.56) | CCNCCDK8CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL30494427 | 0.76 | CCNC (0.56) | CCNCCDK8CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL26463099 | 0.76 | CCNC (0.56) | CCNCCDK8CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL17909801 | 0.75 | PI4K2A (0.50) | CCNCCDK8PI4K2AIKBKBCHUK | |
| SCHEMBL31280998 | 0.75 | CCNC (1.00) | CCNCCDK8CDK19 | |
| SCHEMBL578834 | 0.75 | AR (0.58) | CCNCCDK8PI4K2AARPRKCQ | |
| SCHEMBL28644510 | 0.75 | CCNC (1.00) | CCNCCDK8CDK19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111072634-B | 1-substituted-3-substituted-5-substituted amide-1H-indole compound and preparation method and application thereof | 中国医科大学 | 2022-07-22 | — | — | CN | claimed |