SCHEMBL29941194

SCHEMBL29941194

Cc1ccccc1[C@H]1CCCN1

nearest known ligand 0.55

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 2/20 0.52
CHRM2 P08172 5/20 0.47
CHRM5 P08912 5/20 0.47
CHRM3 P20309 5/20 0.47
CHRM4 P08173 4/20 0.47
CHRM1 P11229 4/20 0.47
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
CHRNB2 P17787 1/20 0.43
CHRNA7 P36544 1/20 0.43
CHRNA4 P43681 1/20 0.43
TAAR1 Q96RJ0 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23323100 1.00 HTR2C (0.52) HTR2CCHRM2CHRM5CHRM3CHRM4
SCHEMBL31444509 1.00 HTR2C (0.52) HTR2CCHRM2CHRM5CHRM3CHRM4
SCHEMBL29747537 1.00 HTR2C (0.52) HTR2CCHRM2CHRM5CHRM3CHRM4
SCHEMBL3331668 1.00 HTR2C (0.52) HTR2CCHRM2CHRM5CHRM3CHRM4
Hydrochloric Acid SCHEMBL31648861 0.98 HTR2C (0.53) HTR2CCHRM2CHRM5CHRM3CHRM4
SCHEMBL13451469 0.94 HTR2C (0.50) HTR2CCHRM2CHRM5CHRM3CHRM4
SCHEMBL17304029 0.94 HTR2C (0.50) HTR2CCHRM2CHRM5CHRM3CHRM4
SCHEMBL2706383 0.94 HTR2C (0.50) HTR2CCHRM2CHRM5CHRM3CHRM4
SCHEMBL7672097 0.93 HTR2C (0.49) HTR2CCHRM2CHRM5CHRM3CHRM4
Hydrochloric Acid SCHEMBL15284187 0.93 HTR2C (0.51) HTR2CCHRM2CHRM5CHRM3CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11446398-B2 Regulated biocircuit systems OBSIDIAN THERAPEUTICS, INC. (US) 2022-09-20 US disclosed