Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 6/20 | 0.48 |
| ▸ | AKT1 | P31749 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 2/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.39 |
| ▸ | FYN | P06241 | 3/20 | 0.39 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CSK | P41240 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.39 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.39 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.39 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.39 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14982761 | 0.87 | SRC (0.53) | SRCAKT1ABL1FYNRIPK2 | |
| SCHEMBL14982760 | 0.78 | SRC (0.70) | SRCAKT1NTRK1ADRA1A | |
| SCHEMBL30175068 | 0.78 | SRC (0.78) | SRCAKT1ABL1FYNRIPK2 | |
| SCHEMBL30429079 | 0.78 | SRC (0.78) | SRCAKT1ABL1FYNRIPK2 | |
| SCHEMBL12436052 | 0.78 | SRC (0.78) | SRCAKT1ABL1FYNRIPK2 | |
| SCHEMBL726813 | 0.68 | SRC (0.64) | SRCAKT1ABL1FYNRIPK2 | |
| SCHEMBL1318810 | 0.67 | SRC (0.79) | SRCAKT1ABL1FYNRIPK2 | |
| SCHEMBL21475580 | 0.67 | GRM5 (0.49) | FYNCYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL14982758 | 0.66 | SRC (0.68) | SRCABL1NTRK1FYN | |
| SCHEMBL14584045 | 0.66 | SRC (0.33) | SRCABL1FYNRIPK2PRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11446398-B2 | Regulated biocircuit systems | OBSIDIAN THERAPEUTICS, INC. (US) | 2022-09-20 | — | — | US | disclosed |