Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 16/20 | 0.45 |
| ▸ | CRBN | Q96SW2 | 16/20 | 0.45 |
| ▸ | WNT1 | P04628 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | IKZF2 | Q9UKS7 | 2/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28947554 | 1.00 | DDB1 (0.45) | DDB1CRBNWNT1GSK3BDYRK1A | |
| SCHEMBL24125715 | 0.87 | DDB1 (0.46) | DDB1CRBNIKZF2 | |
| SCHEMBL24125934 | 0.86 | DDB1 (0.58) | DDB1CRBN | |
| SCHEMBL25173024 | 0.86 | DDB1 (0.52) | DDB1CRBNIKZF2 | |
| Hydrochloric Acid SCHEMBL23301180 | 0.86 | DDB1 (0.46) | DDB1CRBNIKZF2 | |
| Hydrochloric Acid SCHEMBL30376943 | 0.86 | DDB1 (0.46) | DDB1CRBNIKZF2 | |
| SCHEMBL23301396 | 0.86 | DDB1 (0.52) | DDB1CRBNIKZF2 | |
| SCHEMBL25168320 | 0.86 | DDB1 (0.52) | DDB1CRBNIKZF2 | |
| Hydrochloric Acid SCHEMBL25173021 | 0.86 | DDB1 (0.46) | DDB1CRBNIKZF2 | |
| SCHEMBL23551734 | 0.82 | DDB1 (0.60) | DDB1CRBNWNT1GSK3BDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4051674-A1 | BIFUNCTIONAL COMPOUNDS FOR THE TREATMENT OF CANCER | F. Hoffmann-La Roche AG (CH) | 2022-09-07 | — | — | EP | disclosed |