Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKZF2 | Q9UKS7 | 9/20 | 0.55 |
| ▸ | IKZF1 | Q13422 | 3/20 | 0.55 |
| ▸ | CRBN | Q96SW2 | 8/20 | 0.51 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.51 |
| ▸ | GSPT1 | P15170 | 2/20 | 0.46 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.46 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23357974 | 1.00 | IKZF2 (0.55) | IKZF2IKZF1CRBNCSNK1A1GSPT1 | |
| SCHEMBL23358122 | 0.95 | IKZF2 (0.53) | IKZF2IKZF1CRBNCSNK1A1GSPT1 | |
| SCHEMBL29944379 | 0.95 | IKZF2 (0.53) | IKZF2IKZF1CRBNCSNK1A1GSPT1 | |
| SCHEMBL29944409 | 0.93 | IKZF2 (0.60) | IKZF2IKZF1CRBNCSNK1A1GSPT1 | |
| SCHEMBL23357936 | 0.93 | IKZF2 (0.60) | IKZF2IKZF1CRBNCSNK1A1GSPT1 | |
| SCHEMBL23357975 | 0.92 | CRBN (0.56) | IKZF2IKZF1CRBNCSNK1A1GSPT1 | |
| SCHEMBL23358073 | 0.92 | CRBN (0.55) | IKZF2IKZF1CRBNCSNK1A1GSPT1 | |
| SCHEMBL29944410 | 0.92 | IKZF1 (0.49) | IKZF2IKZF1CRBNCSNK1A1GSPT1 | |
| SCHEMBL23357960 | 0.92 | IKZF1 (0.49) | IKZF2IKZF1CRBNCSNK1A1GSPT1 | |
| SCHEMBL23357902 | 0.91 | IKZF2 (0.50) | IKZF2IKZF1CRBNCSNK1A1GSPT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4061812-B1 | COMPOUNDS USEFUL AS INHIBITORS OF HELIOS PROTEIN | BRISTOL MYERS SQUIBB CO (US) | 2026-03-25 | — | — | EP | claimed |
| CN-114728950-B | Compounds useful as inhibitors of HELIOS proteins | 百时美施贵宝公司 | 2024-10-18 | — | — | CN | claimed |
| EP-4061812-A1 | COMPOUNDS USEFUL AS INHIBITORS OF HELIOS PROTEIN | Bristol-Myers Squibb Company (US) | 2022-09-28 | — | — | EP | claimed |
| EP-4061812-B1 | COMPOUNDS USEFUL AS INHIBITORS OF HELIOS PROTEIN | BRISTOL MYERS SQUIBB CO (US) | 2026-03-25 | — | — | EP | disclosed |
| CN-114728950-B | Compounds useful as inhibitors of HELIOS proteins | 百时美施贵宝公司 | 2024-10-18 | — | — | CN | disclosed |
| EP-4061812-A1 | COMPOUNDS USEFUL AS INHIBITORS OF HELIOS PROTEIN | Bristol-Myers Squibb Company (US) | 2022-09-28 | — | — | EP | disclosed |