⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9517639 | 0.98 | CYP1A2 (0.31) | — | |
| SCHEMBL3001662 | 0.91 | — | — | |
| SCHEMBL11021571 | 0.86 | HSD17B10 (0.34) | — | |
| SCHEMBL10760869 | 0.84 | HSD17B10 (0.34) | — | |
| SCHEMBL10765088 | 0.80 | — | — | |
| SCHEMBL5715444 | 0.78 | GRIN1 (0.34) | — | |
| SCHEMBL5200034 | 0.78 | GRIN1 (0.34) | — | |
| SCHEMBL2989826 | 0.77 | — | — | |
| SCHEMBL6756605 | 0.72 | CDK5 (0.35) | — | |
| SCHEMBL2999413 | 0.72 | HSD17B10 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8230986-B2 | Torque limiter | JTEKT CORPORATION (JP) | 2012-07-31 | — | — | US | disclosed |
| US-8220609-B2 | Torque limiter | JTEKT CORPORATION (JP) | 2012-07-17 | — | — | US | disclosed |
| US-20100184519-A1 | TORQUE LIMITER | JTEKT CORPORATION (JP) | 2010-07-22 | — | — | US | disclosed |
| US-20090173591-A1 | TORQUE LIMITER | JTEKT CORPORATION (JP) | 2009-07-09 | — | — | US | disclosed |